Project | 01
Cortical and striatal contributions to inflexible alcohol drinking
We are using a chemogenetic approach to determine the contribution of neural pathways and neuronal populations to inflexible, aversion-resistant alcohol drinking.
Project | 02
Dopaminergic contributions to behavioral flexibility
We are exploring the role of dopamine in reversal learning and punished reward-seeking.
Project | 03
Neural mechanisms of opioid reward and aversion
We are using chemogenetics and immunohistochemistry to explore the contribution of VTA neurons to opioid-mediated reward and aversion. This work is funded through internal grants from Miami University.
Project | 04
Early life stress model of co-morbid PTSD and alcohol use disorder
In collaboration with Dr. Jennifer Quinn, we are investigating how exposure to a traumatic event in infancy can enhance fear-learning and alcohol-drinking.